Synthesis and physicochemical and immunological characterization of pneumococcus type 12F polysaccharide-diphtheria toxoid conjugates
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چکیده
منابع مشابه
synthesis and characterization of some macrocyclic schiff bases
ماکروسیکلهای شیف باز از اهمیت زیادی در شیمی آلی و دارویی برخوردار می باشند. این ماکروسیکلها با دارابودن گروه های مناسب در مکانهای مناسب می توانند فلزاتی مثل مس، نیکل و ... را در حفره های خود به دام انداخته، کمپلکسهای پایدار تولید نمایند. در این پایان نامه ابتدا یک دی آلدئید آروماتیک از گلیسیرین تهیه می شود و در مرحله بعدی واکنش با دی آمینهای آروماتیک و یا آلیفاتیک در رقتهای بسیار زیاد منجر به ت...
15 صفحه اولsynthesis, characterization and immunological properties of escherichia coli 0157:h7 lipopolysaccharide- diphtheria toxoid conjugate vaccine
background and objective: escherichia coli o157:h7, an emerging pathogen, causes severe enteritis and the extraintestinal complication of hemolytic-uremic syndrome. the goal of this study was to evaluate the conjugate of e. coli o157: h7 lipopolysaccharide (lps) with diphtheria toxoid (dt) as a candidate vaccine in mice model. material and methods: lps from e. coli o157:h7 was extracted by hot ...
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Manufacturing new Hepatitis B virus vaccines, specifically by the use of nanoparticles, is of high global interest. In this paper, a new biocompatible and biodegradable structure of nano-sized hepatitis B virus’ surface antigen (HBsAg) was generated by conjugation with dendrimers, a low cost biodegradable and biocompatible polymer. The physicochemical properties of the conjugate were characteri...
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BACKGROUND AND OBJECTIVE Escherichia coli O157:H7, an emerging pathogen, causes severe enteritis and the extraintestinal complication of hemolytic-uremic syndrome. The goal of this study was to evaluate the conjugate of E. coli O157: H7 lipopolysaccharide (LPS) with diphtheria toxoid (DT) as a candidate vaccine in mice model. MATERIAL AND METHODS LPS from E. coli O157:H7 was extracted by hot ...
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Introduction: An effective vaccine against HCV infection is not available. The non-structural protein 3 (NS3) of the virus as an important immunogenic candidate has been utilized in various modules. Nanostructured polymers have been recently used for efficient vaccine and drug delivery. The aim of the current study was the synthesis of rNS3-G2 conjugate and preliminary evaluation of its immunog...
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ژورنال
عنوان ژورنال: Infection and Immunity
سال: 1988
ISSN: 0019-9567,1098-5522
DOI: 10.1128/iai.56.9.2292-2298.1988